An abundance of evidence shows health outcomes and experiences to be different for women and men, and this is true across time, space, and culture. The impact of biological sex accounts for a fraction of these differences; gender explains the rest. Gender refers to the social phenomena and relationships of males and females in terms of their roles, attributes, and opportunities. In health and otherwise, advantage and privilege are largely the domain of maleness and men. That gender is socially constructed means these injustices can change.